MLK3(Phospho Thr277+Ser281) Rabbit Polyclonal Antibody, 50ul sgRNA customized design Loss of the encoded protein

Loss of the encoded protein results in cell proliferation and cancer formation

This gene is co-transcribed with the U69 small nucleolar RNA gene

The heavy chain also interacts with hyaluronan

which promotes binding by heat shock protein 90

RICH1 is a GTPase-activating protein (GAP)

MLK3(Phospho Thr277+Ser281) Rabbit Polyclonal Antibody, 50ul sgRNA customized design Loss of the encoded proteinThe protein encoded by this gene is a member of the serine threonine kinase family. This kinase contains a SH3 domain and a leucine zipper basic motif. This kinase preferentially activates MAPK8 JNK kinase and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate and activates IkappaB kinase alpha and beta and is found to be involved in the transcription activity of NF kappaB mediated by Rho family GTPases