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Cdc25A(Phospho Ser75) Polyclonal Antibody, 100ul Liquid Storage Consumables CRKL encodes a protein kinase

SKU: 3771764634

4.3
PLN141.00 PLN180.00

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Cdc25A(Phospho Ser75) Polyclonal Antibody, 100ul Liquid Storage Consumables CRKL encodes a protein kinaseCDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated.

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Description

CRKL encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion

MARK proteins phosphorylate MAPs within their microtubule binding domains

The gene encodes a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium

proteins and membranes are transported to the endosome where they are sorted for recycling or degradation

while the re-sealable bag keeps them safe and organized

Cdc25A(Phospho Ser75) Polyclonal Antibody, 100ul Liquid Storage Consumables CRKL encodes a protein kinaseCDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated.

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