BID (Cleaved-Arg71) Rabbit Polyclonal Antibody, 100ul Stepper RIMKLB is a Protein Coding

RIMKLB is a Protein Coding gene

Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6

This gene encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation

Mutations in AASS are associated with familial hyperlysinemia

and in derived large-cell lymphomas

BID (Cleaved-Arg71) Rabbit Polyclonal Antibody, 100ul Stepper RIMKLB is a Protein CodingIntact BH3 motif is required by BIK BID BAK BAD and BAX for their pro apoptotic activity and for their interaction with anti apoptotic members of the Bcl 2 family. The major proteolytic product p15 BID allows the release of cytochrome c (By similarity). Isoform 1 isoform 2 and isoform 4 induce ICE like proteases and apoptosis. Isoform 3 does not induce apoptosis. Counters the protective effect of Bcl 2. PTM: Phosphorylated upon DNA damage probably by