Rictor Monoclonal Antibody, 50ul[BT-MCA1103] ADME The protein product contains a

The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor

The PIAS family contains a conserved RING domain that has been linked to a function as a small ubiquitin-related modifier (SUMO) ligase

an autosomal dominant multisystemic vascular dysplasia

It is localized to the cell membrane via a pleckstrin homology (PH) domain in the C-terminal region

A specific kinase phosphorylates amino acids in this same C-terminal region and the expression of this kinase is upregulated during pathogenesis

Rictor Monoclonal Antibody, 50ul[BT-MCA1103] ADME The protein product contains aRICTOR and MTOR (FRAP1 MIM 601231) are components of a protein complex that integrates nutrient and growth factor derived signals to regulate cell growth (Sarbassov et al., 2004 [PubMed 15268862]).[supplied by OMIM, Mar 2008],