IDUA Polyclonal Antibody, 20ul Biochemical Reagents The encoded enzyme catalyzes the

The encoded enzyme catalyzes the hydrolysis of acyloxylacyl-linked fatty acyl chains from bacterial lipopolysaccharides

generates a transcript (SALF)

and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins

and five C2H2-type zinc finger motifs

Down-regulated in immortalized fibroblasts isolated after a proliferative crisis accompanied with massive cell death

IDUA Polyclonal Antibody, 20ul Biochemical Reagents The encoded enzyme catalyzes theThis gene encodes an enzyme that hydrolyzes the terminal alpha L iduronic acid residues of two glycosaminoglycans dermatan sulfate and heparan sulfate. This hydrolysis is required for the lysosomal degradation of these glycosaminoglycans. Mutations in this gene that result in enzymatic deficiency lead to the autosomal recessive disease mucopolysaccharidosis type I (MPS I).