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IκB alpha(Phospho-Ser32) Rabbit Polyclonal Antibody, 50ul Erlenmeyer Flasks The encoded secreted protein is

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IκB alpha(Phospho-Ser32) Rabbit Polyclonal Antibody, 50ul Erlenmeyer Flasks The encoded secreted protein isThis gene encodes a member of the NF kappa B inhibitor family which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell

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Description

The encoded secreted protein is involved in the formation of a gel matrix that encases ejaculated spermatozoa

The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36

Naturally-occurring readthrough transcription may occur from the upstream SETDB2 (SET domain bifurcated 2) gene to this locus

Plays a role in transcriptional activation of Wnt-responsive genes

This protein has also been reported to modify RNA by adding a methylthio-group and may thus have a dual function as an RNA methylthiotransferase and as an inhibitor of cyclin-dependent kinase 5 activity

IκB alpha(Phospho-Ser32) Rabbit Polyclonal Antibody, 50ul Erlenmeyer Flasks The encoded secreted protein isThis gene encodes a member of the NF kappa B inhibitor family which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell

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