PTP IA-2Beta Polyclonal Antibody, 50ul Dry Bath consisting of three different polypeptide

consisting of three different polypeptide chains (alpha

TOP2B encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in TOP2B have been associated with the development of drug resistance

It is active on peptide linkages involving the carboxyl group of lysine or arginine

Decreased activity of the encoded enzyme may be associated with the disease D-glyceric aciduria

DUF1220 copy number variations in human chromosomal region 1q21

PTP IA-2Beta Polyclonal Antibody, 50ul Dry Bath consisting of three different polypeptidePTPRN2 (protein tyrosine phosphatase, receptor type N2) encodes a protein with sequence similarity to receptor like protein tyrosine phosphatases. However, tyrosine phosphatase activity has not been experimentally validated for this protein. Studies of the rat ortholog suggest that the encoded protein may instead function as a phosphatidylinositol phosphatase with the ability to dephosphorylate phosphatidylinositol 3 phosphate and phosphatidylinositol