HXC9 Polyclonal Antibody, 100ul Peripheral Blood Separation Tube The protein encoded by NLRX1

The protein encoded by NLRX1 (NLR family member X1) is a member of the NLR family and localizes to the outer mitochondrial membrane

It also interacts with and is phosphoryated by serine/threonine kinase 25

Gene Ontology (GO) annotations related to this gene include chromatin binding and protein complex binding

Overexpression of this gene suppresses the activation of NF-kappa B induced by TNFRSF9 or TNF receptor-associated factor 2 (TRAF2)| which suggests that this protein is a negative regulator of TNFRSF9-mediated signaling cascades

This kinase is also involved in UV radiation induced apoptosis

HXC9 Polyclonal Antibody, 100ul Peripheral Blood Separation Tube The protein encoded by NLRX1This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on