Histone H2A.Z Polyclonal Antibody, 50ul[BT-AP04008] Cellular Function Assays Homotetramers consisting of a proteolytically

Homotetramers consisting of a proteolytically cleaved form of the protein| or type A subunit| exhibit low affinity for heparin and do not interact with the ECM

Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML)

Amplification and overexpression of this gene have been observed in several types of human carcinomas

The protein precursor is further processed into an active mature peptide

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Histone H2A.Z Polyclonal Antibody, 50ul[BT-AP04008] Cellular Function Assays Homotetramers consisting of a proteolyticallyHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.