WDR36 Rabbit Polyclonal Antibody, 50ul Measuring Instruments Two main isozymes are known

Two main isozymes are known to exist in eukaryotic cells: one is found in the mitochondrial matrix and the other in the cytoplasm

This gene encodes a member of a family of proteins that possess a 100-amino acid PDZ domain at the N terminus and one to three LIM domains at the C-terminus

and is thought to primarily function in the control of the germline meiotic cell cycle

The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing

Different isoforms of this protein may regulate inducible expression of different cytokine genes

WDR36 Rabbit Polyclonal Antibody, 50ul Measuring Instruments Two main isozymes are knownThis gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly his and trp asp (GH WD) which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes including cell cycle progression signal transduction apoptosis and gene regulation. Mutations in this gene have been