JAK3(Phospho Tyr785) Polyclonal Antibody, 50ul Deep Well Plates The protein localizes to membrane

The protein localizes to membrane protrusions and is often expressed on adult stem cells

The encoded protein interacts with CD3-zeta (CD247)

it lacks domain VI

Involved in accumulation of zinc in synaptic vesicles

but the full-length nature of these variants has not been determined

JAK3(Phospho Tyr785) Polyclonal Antibody, 50ul Deep Well Plates The protein localizes to membraneThe protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).