FAS(Phospho Tyr291) Polyclonal Antibody, 50ul Diagnostic Probes & Oligos Targeted disruption of the related

Targeted disruption of the related gene in mice led to severe osteopetrosis and a lack of osteoclasts

It contains N-terminal transmembrane helices and a long C-terminal cytoplasmic tail with serine/threonine/tyrosine kinase activity

The antigen is being used as a target for immunotherapy treatment of human carcinomas

The protein encoded by this gene is a bifunctional

type II (IL1R2) and interleukin 1 receptor-like 2 (IL1RL2) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12

FAS(Phospho Tyr291) Polyclonal Antibody, 50ul Diagnostic Probes & Oligos Targeted disruption of the relatedThe protein encoded by this gene is a member of the TNF receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death inducing signaling complex that includes Fas associated