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ATOH7 Polyclonal Antibody, 100ul RNA Synthesis multiple putative phosphorylation sites

SKU: 3543736121

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ATOH7 Polyclonal Antibody, 100ul RNA Synthesis multiple putative phosphorylation sitesThis intronless gene encodes a member of the basic helix loop helix family of transcription factors, with similarity to Drosophila atonal gene that controls photoreceptor development. Studies in mice suggest that this gene plays a central role in retinal ganglion cell and optic nerve formation. Mutations in this gene are associated with nonsyndromic congenital retinal nonattachment.

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Description

multiple putative phosphorylation sites

at least one of which encodes a preproprotein is proteolytically processed to generate a calcium-dependent cell adhesion molecule and glycoprotein

including tumor suppressor proteins p53 and BRCA1

This protein shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro

Polymorphisms in this gene are associated with susceptibility to gastric cancers

ATOH7 Polyclonal Antibody, 100ul RNA Synthesis multiple putative phosphorylation sitesThis intronless gene encodes a member of the basic helix loop helix family of transcription factors, with similarity to Drosophila atonal gene that controls photoreceptor development. Studies in mice suggest that this gene plays a central role in retinal ganglion cell and optic nerve formation. Mutations in this gene are associated with nonsyndromic congenital retinal nonattachment.

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