FHL3 Polyclonal Antibody, 100ul Lysosome which is a member of

which is a member of the 7 transmembrane-spanning G protein-coupled receptor family

May also be involved in the regulation of gene expression

IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al

In addition| protein levels decrease in the presence of natural killer lytic-associated molecule| suggesting that association with natural killer lytic-associated molecule results in ubiquitination and subsequent degradation of this protein

The exact role of this gene has not been determined

FHL3 Polyclonal Antibody, 100ul Lysosome which is a member ofThe protein encoded by this gene is a member of a family of proteins containing a four and a half LIM domain, which is a highly conserved double zinc finger motif. The encoded protein has been shown to interact with the cancer developmental regulators SMAD2, SMAD3, and SMAD4, the skeletal muscle myogenesis protein MyoD, and the high affinity IgE beta chain regulator MZF 1. This protein may be involved in tumor suppression, repression of MyoD