Granuphilin Polyclonal Antibody, 20ul Endonucleases & Exonucleases GIT1 contains an ARFGAP domain

GIT1 contains an ARFGAP domain

a chemokine which specifically mediates monocyte chemotaxis

Alternatively spliced transcript variants encoding distinct isoforms have been identified

which bind microtubules

Mutations in this gene cause Alexander disease

Granuphilin Polyclonal Antibody, 20ul Endonucleases & Exonucleases GIT1 contains an ARFGAP domainSYTL4 (synaptotagmin like 4) encodes a member of the synaptotagmin like protein family. Members of this family are characterized by an N terminal Rab27 binding domain and C terminal tandem C2 domains. The encoded protein binds specific small Rab GTPases and is involved in intracellular membrane trafficking. This protein binds Rab27 and may be involved in inhibiting dense core vesicle exocytosis. Alternate splicing results in multiple transcript