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HIF-1 Beta/ARNT Monoclonal Antibody(4C5), 20ul Nucleic Acid Amplification Studies of a similar gene

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HIF-1 Beta/ARNT Monoclonal Antibody(4C5), 20ul Nucleic Acid Amplification Studies of a similar geneThis gene encodes a protein containing a basic helix loop helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co factor for transcriptional regulation by hypoxia inducible factor 1. Chromosomal translocation

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Description

Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease

ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA

YAP2 encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development

the protein encoded by DYSF binds caveolin-3

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HIF-1 Beta/ARNT Monoclonal Antibody(4C5), 20ul Nucleic Acid Amplification Studies of a similar geneThis gene encodes a protein containing a basic helix loop helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co factor for transcriptional regulation by hypoxia inducible factor 1. Chromosomal translocation

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