M-CSF Receptor(Phospho-Tyr546) Rabbit Polyclonal Antibody, 20ul Pipette Controller ITGA3 (integrin subunit alpha 3)

ITGA3 (integrin subunit alpha 3) encodes a member of the integrin alpha chain family of proteins

based on the arrangement of the first 2 of the 4 conserved cysteine residues

It is predominantly expressed in the pituitary gland

this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias

the binding site for calmodulin

M-CSF Receptor(Phospho-Tyr546) Rabbit Polyclonal Antibody, 20ul Pipette Controller ITGA3 (integrin subunit alpha 3)The protein encoded by this gene is the receptor for colony stimulating factor 1 a cytokine which controls the production differentiation and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1 PDGF