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ABCC8 Polyclonal Antibody, 50ul Cell Screening and Imaging RAN coactivation of the AR

SKU: 33689605364

4.6
USD185.00 USD224.00

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ABCC8 Polyclonal Antibody, 50ul Cell Screening and Imaging RAN coactivation of the ARThe protein encoded by this gene is a member of the superfamily of ATP binding cassette (ABC) transporters. ABC proteins transport various molecules across extra and intra cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1 MDR TAP MRP ALD OABP GCN20 White). This protein is a member of the MRP subfamily which is involved in multi drug resistance. This protein functions as a modulator of ATP sensitive potassium channels and

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Description

RAN coactivation of the AR diminishes with polyglutamine expansion within the AR

Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of p16(INK4a)

Interacts with TIPIN

Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system

The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit

ABCC8 Polyclonal Antibody, 50ul Cell Screening and Imaging RAN coactivation of the ARThe protein encoded by this gene is a member of the superfamily of ATP binding cassette (ABC) transporters. ABC proteins transport various molecules across extra and intra cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1 MDR TAP MRP ALD OABP GCN20 White). This protein is a member of the MRP subfamily which is involved in multi drug resistance. This protein functions as a modulator of ATP sensitive potassium channels and

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