CI072 Rabbit Polyclonal Antibody, 20ul Thermo Mix Ankyrin repeat and protein kinase

Ankyrin repeat and protein kinase domain-containing protein 1 encoded by ANKK1 belongs to the Ser/Thr protein kinase family

May act as a tumor suppressor

and a cytoplasmic domain

2009 [PubMed 19481526])

Mutations in F2 lead to various forms of thrombosis and dysprothrombinemia

CI072 Rabbit Polyclonal Antibody, 20ul Thermo Mix Ankyrin repeat and protein kinaseThe protein encoded by this gene plays an important role in the regulation of endosomal trafficking, and has been shown to interact with Rab proteins that are involved in autophagy and endocytic transport. Expansion of a GGGGCC repeat from 2 22 copies to 700 1600 copies in the intronic sequence between alternate 5' exons in transcripts from this gene is associated with 9p linked ALS (amyotrophic lateral sclerosis) and FTD (frontotemporal dementia)