TRY6 Rabbit Polyclonal Antibody, 50ul Glassware Sets Paralogous members of the riboflavin

Paralogous members of the riboflavin transporter gene family are located on chromosomes 17 and 20

FABPs may play roles in fatty acid uptake

This is supported by studies in knockout mice showing development of soft-tissue sarcomas| ovarian stromal cell tumors and a high sensitivity to carcinogenic treatmen

The encoded protein also functions as a scaffold protein mediating membrane localization of phosphorylated protein kinase B

The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex

TRY6 Rabbit Polyclonal Antibody, 50ul Glassware Sets Paralogous members of the riboflavinAlthough this locus appears to encode a protein similar to trypsinogen the locus is thought to be a transcribed pseudogene. ESTs support its transcription but expression of its predicted protein has not been observed. Its predicted protein sequence differs significantly from the known functional trypsinogens including a different amino acid at the conserved residue 122 which is important for autolysis. This pseudogene and several other trypsinogen