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EID-1 Polyclonal Antibody, 50ul Cell Biology Knockout mouse studies show defects

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EID-1 Polyclonal Antibody, 50ul Cell Biology Knockout mouse studies show defectsE1A like inhibitor of differentiation 1 (EID 1), an acetyltransferase enzyme, binds both the retinoblastoma protein (Rb), a regulator of cell cycle and tissue specific transcription, and the adenovirus E1A associated cellular p300 transcriptional co activator protein. EID 1 inhibits cellular differentiation by blocking the histone acetyltransferase activity of p300. EID 1 also acetylates both histones and non histone proteins such as NCOA3 co

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Description

Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures

Proteolytic processing of this protein gives rise to an N-terminal fragment that contains the four leucine-rich repeats and five epidermal growth factor repeats and a C-terminal fragment that contains four epidermal growth factor repeats and the cysteine knot

Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma

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BAM32 interacts with Ptdlns and PLC g2 and

EID-1 Polyclonal Antibody, 50ul Cell Biology Knockout mouse studies show defectsE1A like inhibitor of differentiation 1 (EID 1), an acetyltransferase enzyme, binds both the retinoblastoma protein (Rb), a regulator of cell cycle and tissue specific transcription, and the adenovirus E1A associated cellular p300 transcriptional co activator protein. EID 1 inhibits cellular differentiation by blocking the histone acetyltransferase activity of p300. EID 1 also acetylates both histones and non histone proteins such as NCOA3 co

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