MDMX(Phospho Ser367) Polyclonal Antibody, 50ul Immunoassays and likely other mammals as

and likely other mammals as well

which is abundant in the eukaryotic cytosol and may be involved in the transport and assembly of newly synthesized proteins

This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator

most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development

tissue specificity:Highly expressed in surface mucosal cells of respiratory tract and stomach epithelia

MDMX(Phospho Ser367) Polyclonal Antibody, 50ul Immunoassays and likely other mammals asThis gene encodes a nuclear protein that contains a p53 binding domain at the N terminus and a RING finger domain at the C terminus, and shows structural similarity to p53 binding protein MDM2. Both proteins bind the p53 tumor suppressor protein and inhibit its activity, and have been shown to be overexpressed in a variety of human cancers. However, unlike MDM2 which degrades p53, this protein inhibits p53 by binding its transcriptional activation