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p27(Phospho Ser178) Polyclonal Antibody, 20ul DNA Fragments Paired box transcription factors are

SKU: 31775131797

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SEK111.00 SEK133.00

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p27(Phospho Ser178) Polyclonal Antibody, 20ul DNA Fragments Paired box transcription factors areThis gene encodes a cyclin dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A p21. The encoded protein binds to and prevents the activation of cyclin E CDK2 or cyclin D CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from

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Description

Paired box transcription factors are important regulators in early development

It also interacts with other transcription factors

Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors

or with the TAF15 gene on chromosome 17

The encoded protein (eomesodermin) is a transcription factor which is crucial for embryonic development of mesoderm and the central nervous system in vertebrates

p27(Phospho Ser178) Polyclonal Antibody, 20ul DNA Fragments Paired box transcription factors areThis gene encodes a cyclin dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A p21. The encoded protein binds to and prevents the activation of cyclin E CDK2 or cyclin D CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from

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