Cytokeratin 18 Monoclonal Antibody(1B3), 100ul Biochemical Reagents alpha2(VI)

alpha2(VI)

and have been found in one case of early onset hypertrophic cardiomyopathy and encephalopathy

This protein may be involved in tumor suppression

This gene is also involved in several chromosomal translocations that are associated with lymphoid malignancies including pre-B-cell acute lymphoblastic leukemia (t(1|19)

and yeast Ste11

Cytokeratin 18 Monoclonal Antibody(1B3), 100ul Biochemical Reagents alpha2(VI)KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.