Nrf2 Polyclonal Antibody, 20ul[BT-AP06175] ADME Mutations in this gene result

Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions

Involved in the regulation of structural processes in differentiating and mature neuronal cells

Alternate allele-specific splice variants

and organ morphology and function

Mutations in SPTAN1 are the cause of early infantile epileptic encephalopathy-5

Nrf2 Polyclonal Antibody, 20ul[BT-AP06175] ADME Mutations in this gene resultNFE2L2 encodes a transcription factor (nuclear factor, erythroid 2 like 2) which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different