GFAP Monoclonal Antibody, 50ul Centrifugal Filter TMC8 encodes a transmembrane channel-like

TMC8 encodes a transmembrane channel-like protein with 8 predicted transmembrane domains and 3 leucine zipper motifs

Mutations in this gene are associated with Bethlem myopathy and Ullrich scleroatonic muscular dystrophy

and is thought to function as an ATP-dependent RNA helicase that regulates the release of spliced mRNAs from spliceosomes prior to their export from the nucleus

With the hydrolysis of ATP by NSF

An important paralog of this gene is YWHAZ

GFAP Monoclonal Antibody, 50ul Centrifugal Filter TMC8 encodes a transmembrane channel-likeThis gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.