Catenin-Beta Polyclonal Antibody, 50ul[BT-AP01230] Cell Culture & Maintenance Down-regulation of this gene has

Down-regulation of this gene has been associated with a variety of human epithelial malignancies

This protein may also play a role in maintaining the membrane permeability barrier| and knockdown of this gene in human cells results in the release of cytochrome c and apoptosis

while the soluble form has only the catalytic domain

thyroid hormone receptor- (TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors

This gene encodes one of three related filamin genes| specifically gamma filamin

Catenin-Beta Polyclonal Antibody, 50ul[BT-AP01230] Cell Culture & Maintenance Down-regulation of this gene hasThe protein (catenin beta 1) encoded by CTNNB1 is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete.