PUMA Polyclonal Antibody, 50ul Centrifuges Belongs to the PRPF40 family

Belongs to the PRPF40 family

The protein encoded by MCM3AP (minichromosome maintenance complex component 3 associated protein) is a MCM3 binding protein

This proto-oncogene may play a role in the regulation of embryonic development and cell growth

which suggests a role in the JNK signaling pathway

This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18

PUMA Polyclonal Antibody, 50ul Centrifuges Belongs to the PRPF40 familyBBC3 encodes a member of the BCL 2 family of proteins. This family member belongs to the BH3 only pro apoptotic subclass. BCL2 binding component 3 cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti apoptotic Bcl 2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro apoptotic role, BBC3 is a potential drug target for cancer