Oct-3/4 Monoclonal Antibody, 100ul[BT-MCA0954] Cell Function Analysis This gene is a candidate

This gene is a candidate gene for autosomal dominant retinitis pigmentosa

particularly of granule cells

Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene

a subunit also shared by the receptor complex for interleukin 10 (IL10)

The encoded protein has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32

Oct-3/4 Monoclonal Antibody, 100ul[BT-MCA0954] Cell Function Analysis This gene is a candidateThis gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non AUG translation initiation