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HLA-DQB1/2 Polyclonal Antibody, 100ul Endonucleases & Exonucleases Mutations in this gene are

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HLA-DQB1/2 Polyclonal Antibody, 100ul Endonucleases & Exonucleases Mutations in this gene areHLA DQB1 belongs to the HLA class II beta chain paralogs. This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: b lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26 28 kDa and it

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Description

Mutations in this gene are associated with autism spectrum disorders

The protein encoded by MCM3AP (minichromosome maintenance complex component 3 associated protein) is a MCM3 binding protein

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity

The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids

The protein encoded by XRCC5 (X-ray repair cross complementing 5) is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5

HLA-DQB1/2 Polyclonal Antibody, 100ul Endonucleases & Exonucleases Mutations in this gene areHLA DQB1 belongs to the HLA class II beta chain paralogs. This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: b lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26 28 kDa and it

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