NUMB Polyclonal Antibody, 50ul Drug Development and Evaluation SH3BGR (SH3 Domain Binding Glutamate

SH3BGR (SH3 Domain Binding Glutamate Rich Protein) is a Protein Coding gene

and stress-induced genes

a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators

It is an ATPase and essential for the catalytic step II in pre-mRNA splicing process

The protein encoded by this gene interacts with several other proteins

NUMB Polyclonal Antibody, 50ul Drug Development and Evaluation SH3BGR (SH3 Domain Binding GlutamateProtein numb homolog encoded by NUMB plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome dependent manner by MDM2, is a membrane bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants.