p53 Polyclonal Antibody, 100ul[BT-AP06829] Mechanical Pipette |NF-kappa-B is a pleiotropic transcription

|NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation| immunity| differentiation| cell growth| tumorigenesis and apoptosis

Mutations in this gene have been associated with susceptibility to obesity and proprotein convertase 1/3 deficiency

Mutations in this gene are the cause of Walker-Warburg syndrome

Overexpression does not disrupt microtubule organization or the integrity of the Golgi but does cause both cytosolic and nuclear distribution

including cell proliferation and migration

p53 Polyclonal Antibody, 100ul[BT-AP06829] Mechanical Pipette |NF-kappa-B is a pleiotropic transcriptionTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.