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p21 Polyclonal Antibody, 20ul[BT-AP12603] Roller Bottles Mice deficient for this gene

SKU: 28499032590

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p21 Polyclonal Antibody, 20ul[BT-AP12603] Roller Bottles Mice deficient for this geneThis gene encodes a potent cyclin dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin cyclin dependent kinase2 or cyclin dependent kinase4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53 dependent cell cycle G1 phase arrest in response to a variety of

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Description

Mice deficient for this gene have increased fat mass despite decreased food intake

as well as non-integrin laminin-binding proteins

This protein is localized to the trans Golgi network

ubiquitin aldehyde binding 2 contains an OTU domain and binds Ubal (ubiquitin aldehyde)

TBX18 codes for a member of an evolutionarily conserved family of transcription factors that plays a crucial role in embryonic development

p21 Polyclonal Antibody, 20ul[BT-AP12603] Roller Bottles Mice deficient for this geneThis gene encodes a potent cyclin dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin cyclin dependent kinase2 or cyclin dependent kinase4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53 dependent cell cycle G1 phase arrest in response to a variety of

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