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Rat Sorbitol Dehydrogenase, SDH ELISA Kit, 96T Hybridoma Antibody Sequencing activated form

SKU: 28400413838

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Rat Sorbitol Dehydrogenase, SDH ELISA Kit, 96T Hybridoma Antibody Sequencing activated formPolyol dehydrogenase that catalyzes the reversible NAD(+) dependent oxidation of various sugar alcohols (By similarity). Is active with D sorbitol (D glucitol) leading to the C2 oxidized product D fructose (PubMed: 6862079). Is a key enzyme in the polyol pathway that interconverts glucose and fructose via sorbitol, which constitutes an important alternate route for glucose metabolism. May play a role in sperm motility by using sorbitol as an

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Description

activated form

and the transcription factors ATF2 (activating transcription factor 2) and c-JUN

The encoded protein can also phosphorylate histone H3 to regulate certain inflammatory genes

Also has anti-fibrotic activity in lung (PubMed: 24213919

These two proteins are so closely related

Rat Sorbitol Dehydrogenase, SDH ELISA Kit, 96T Hybridoma Antibody Sequencing activated formPolyol dehydrogenase that catalyzes the reversible NAD(+) dependent oxidation of various sugar alcohols (By similarity). Is active with D sorbitol (D glucitol) leading to the C2 oxidized product D fructose (PubMed: 6862079). Is a key enzyme in the polyol pathway that interconverts glucose and fructose via sorbitol, which constitutes an important alternate route for glucose metabolism. May play a role in sperm motility by using sorbitol as an

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