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HMG-1 Polyclonal Antibody, 100ul[BT-AP04142] Immunology as well as other aspects

SKU: 28370950453

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HMG-1 Polyclonal Antibody, 100ul[BT-AP04142] Immunology as well as other aspectsHMGB1 encodes high mobility group protein B1 that belongs to the High Mobility Group box superfamily. The encoded non histone, nuclear DNA binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript

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Description

as well as other aspects of mRNA metabolism and transport

The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes

tissue specificity:Expressed abundantly in the lung and neutrophils

Three alternatively spliced transcripts encoding different isoforms have been described

The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events

HMG-1 Polyclonal Antibody, 100ul[BT-AP04142] Immunology as well as other aspectsHMGB1 encodes high mobility group protein B1 that belongs to the High Mobility Group box superfamily. The encoded non histone, nuclear DNA binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript

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