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Dematin(Phospho Ser403) Polyclonal Antibody, 100ul Microbial Genome Editing Mediator is recruited to promoters

SKU: 27884277861

4.3
SEK123.75 SEK167.75

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Dematin(Phospho Ser403) Polyclonal Antibody, 100ul Microbial Genome Editing Mediator is recruited to promotersThe protein encoded by this gene is an actin binding and bundling protein that plays a structural role in erythrocytes, by stabilizing and attaching the spectrin actin cytoskeleton to the erythrocyte membrane in a phosphorylation dependent manner. This protein contains a core domain in the N terminus, and a headpiece domain in the C terminus that binds F actin. When purified from erythrocytes, this protein exists as a trimer composed of two 48 kDa

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Description

Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors

The encoded protein contains three leucine-rich repeat motifs

An important paralog of this gene is ZNF501

and also plays a role in synaptic signaling through interactions with calcium channels

Inducible expression of IRF7 is largely restricted to lymphoid tissue

Dematin(Phospho Ser403) Polyclonal Antibody, 100ul Microbial Genome Editing Mediator is recruited to promotersThe protein encoded by this gene is an actin binding and bundling protein that plays a structural role in erythrocytes, by stabilizing and attaching the spectrin actin cytoskeleton to the erythrocyte membrane in a phosphorylation dependent manner. This protein contains a core domain in the N terminus, and a headpiece domain in the C terminus that binds F actin. When purified from erythrocytes, this protein exists as a trimer composed of two 48 kDa

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