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KCNK4 (TRAAK) Polyclonal Antibody, 50ul Cryopreservation Mutations in this gene cause

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KCNK4 (TRAAK) Polyclonal Antibody, 50ul Cryopreservation Mutations in this gene causeThis gene encodes a member of the TWIK related arachidonic acid stimulated two pore potassium channel subfamily. The encoded protein homodimerizes and functions as an outwardly rectifying channel. This channel is regulated by polyunsaturated fatty acids, temperature and mechanical deformation of the lipid membrane. This protein is expressed primarily in neural tissues and may be involved in regulating the noxious input threshold in dorsal root ganglia

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Description

Mutations in this gene cause X-linked Charcot-Marie-Tooth disease

It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP)

Gene expression is high during fetal development and in most tumors

The protein encoded by LAIR2 is a soluble receptor that may play roles in both inhibition of collagen-induced platelet aggregation and vessel formation during placental implantation

Although this gene has been referred to as RPL10

KCNK4 (TRAAK) Polyclonal Antibody, 50ul Cryopreservation Mutations in this gene causeThis gene encodes a member of the TWIK related arachidonic acid stimulated two pore potassium channel subfamily. The encoded protein homodimerizes and functions as an outwardly rectifying channel. This channel is regulated by polyunsaturated fatty acids, temperature and mechanical deformation of the lipid membrane. This protein is expressed primarily in neural tissues and may be involved in regulating the noxious input threshold in dorsal root ganglia

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