CACB1 Rabbit Polyclonal Antibody, 50ul Glassware Sets which is a coactivator for

which is a coactivator for several nuclear receptors (NRs) and is associated with breast cancer

In humans| this protein has been shown to bind to the adapter insulin receptor substrate 4 (IRS4) to mediate translocation of alpha-5 integrin from the cell membrane to endosomes

Nuclear localization of RAN requires the presence of regulator of chromosome condensation 1 (RCC1)

as well as a hyaluronic acid-binding protein

The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system

CACB1 Rabbit Polyclonal Antibody, 50ul Glassware Sets which is a coactivator forThe protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha 1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified.