CYR61 Polyclonal Antibody, 50ul Cell Culture Dishes Activins signal through a heteromeric

Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors

May function as a transcriptional regulator

and antagonizes glucocorticoid-stimulated gene transcription

but this gene encodes proteins with only a single BIR domain

The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins

CYR61 Polyclonal Antibody, 50ul Cell Culture Dishes Activins signal through a heteromericThe secreted protein encoded by this gene is growth factor inducible and promotes the adhesion of endothelial cells. The encoded protein interacts with several integrins and with heparan sulfate proteoglycan. This protein also plays a role in cell proliferation, differentiation, angiogenesis, apoptosis, and extracellular matrix formation.