Lamin B1 Polyclonal Antibody, 100ul[BT-AP04935] General Lab Use Belongs to the vinculin/alpha-catenin family

Belongs to the vinculin/alpha-catenin family

Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance

It is highly conserved in vertebrates and most abundantly expressed in the brain

The genomic region is also rich in Alu repetitive sequences

Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined

Lamin B1 Polyclonal Antibody, 100ul[BT-AP04935] General Lab Use Belongs to the vinculin/alpha-catenin familyLMNB1 encodes one of the two B type lamin proteins and is a component of the nuclear lamina. A duplication of LMNB1 is associated with autosomal dominant adult onset leukodystrophy (ADLD). Alternative splicing results in multiple transcript variants.