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SQSTM1/p62(Phospho-Ser403) Rabbit Polyclonal Antibody, 50ul Peptide Modification Multiple transcript variants encoding different

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SQSTM1/p62(Phospho-Ser403) Rabbit Polyclonal Antibody, 50ul Peptide Modification Multiple transcript variants encoding differentThis gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa B (NF kB) signaling pathway. The protein functions as a scaffolding adaptor protein in concert with TNF receptor associated factor 6 to mediate activation of NF kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in

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Description

Multiple transcript variants encoding different isoforms have been found for SMARCA4

The encoded protein is a membrane-associated kinase that negatively regulates the G2/M transition of the cell cycle by phosphorylating and inactivating cyclin-dependent kinase 1

An important paralog of this gene is CYB5R3

Mutations in AKT1 have been associated with the Proteus syndrome

The encoded protein (complement C6) is part of the membrane attack complex that can be incorporated into the cell membrane and cause cell lysis

SQSTM1/p62(Phospho-Ser403) Rabbit Polyclonal Antibody, 50ul Peptide Modification Multiple transcript variants encoding differentThis gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa B (NF kB) signaling pathway. The protein functions as a scaffolding adaptor protein in concert with TNF receptor associated factor 6 to mediate activation of NF kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in

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