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DNA pol Beta Polyclonal Antibody, 20ul Pipette Controller increasing efficiency and saving time

SKU: 25873102671

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DNA pol Beta Polyclonal Antibody, 20ul Pipette Controller increasing efficiency and saving timeDNA polymerase beta encoded by POLB is a DNA polymerase involved in base excision and repair, also called gap filling DNA synthesis. The encoded protein, acting as a monomer, is normally found in the cytoplasm, but it translocates to the nucleus upon DNA damage. Several transcript variants of POLB exist, but the full length nature of only one has been described to date.

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Description

increasing efficiency and saving time

Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients

including neurotransmission

and is considered to be an oncogene

The protein is normally found in the membrane of the endoplasmic reticulum

DNA pol Beta Polyclonal Antibody, 20ul Pipette Controller increasing efficiency and saving timeDNA polymerase beta encoded by POLB is a DNA polymerase involved in base excision and repair, also called gap filling DNA synthesis. The encoded protein, acting as a monomer, is normally found in the cytoplasm, but it translocates to the nucleus upon DNA damage. Several transcript variants of POLB exist, but the full length nature of only one has been described to date.

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