NLTP Rabbit Polyclonal Antibody, 50ul Deep Well Plates Alternative splicing of PIK3R1 results

Alternative splicing of PIK3R1 results in four transcript variants encoding different isoforms

transcription activation and apoptosis

The encoded protein circulates in the plasma and is involved with metabolic and hormonal processes

This gene is no longer considered to be a candidate gene for COX deficiency

Transcripts that initiate from an upstream promoter encode alpha isoforms

NLTP Rabbit Polyclonal Antibody, 50ul Deep Well Plates Alternative splicing of PIK3R1 resultsThis gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2) as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein and the transcript initiated from the distal promoter encodes the shorter SCP2 protein with the 2 proteins sharing a common C terminus. Evidence suggests that the SCPx protein is a