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CD58 Polyclonal Antibody, 50ul[BT-AP02487] Cell Senescence deubiquityling enzymes remove ubiquitin

SKU: 25116027371

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CD58 Polyclonal Antibody, 50ul[BT-AP02487] Cell Senescence deubiquityling enzymes remove ubiquitinDRD4 encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in DRD4 have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit hyperactivity disorder, and the personality trait of novelty seeking. DRD4 contains a polymorphic number

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Description

deubiquityling enzymes remove ubiquitin

The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation

This domain is common to a number of hydrolytic enzymes of widely differing phylogenetic origins and catalytic functions

It also functions as a repressor of NF-kappa-B by promoting ubiquitination of the NF-kappa-B subunit RELA in a HAT-independent manner

subcellular location:Colocalizes with nuclear pore complex protein NUP62

CD58 Polyclonal Antibody, 50ul[BT-AP02487] Cell Senescence deubiquityling enzymes remove ubiquitinDRD4 encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in DRD4 have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit hyperactivity disorder, and the personality trait of novelty seeking. DRD4 contains a polymorphic number

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