AIF-M1 Monoclonal Antibody, 50ul Culture Tubes also known as hereditary hyperekplexia

also known as hereditary hyperekplexia or congenital stiff-person syndrome

Pallister-Hall syndrome

A mutation in this gene has been associate

Several alternatively spliced transcript variants have been identified

The encoded protein also is a coreceptor for HIV-1

AIF-M1 Monoclonal Antibody, 50ul Culture Tubes also known as hereditary hyperekplexiaThis gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase 9. Mutations in this gene cause