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PRLR Polyclonal Antibody, 100ul Supplements Mutations in this gene may

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PRLR Polyclonal Antibody, 100ul Supplements Mutations in this gene mayThis gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin dependent signaling occurs as the result of ligand induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of

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Description

Mutations in this gene may be associated with hereditary nonpolyposis colon cancer

Among its related pathways are Metabolism and Respiratory electron transport

a single pass transmembrane region

CASP1 (caspase 1) encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family

A pseudogene of this gene is found on chromosome 2

PRLR Polyclonal Antibody, 100ul Supplements Mutations in this gene mayThis gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin dependent signaling occurs as the result of ligand induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of

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