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p53 Polyclonal Antibody, 50ul[BT-AP06832] Molecular Sciences Numerous pseudogenes have been reported

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p53 Polyclonal Antibody, 50ul[BT-AP06832] Molecular Sciences Numerous pseudogenes have been reportedTP53 (tumor protein p53) encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni

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Description

Numerous pseudogenes have been reported for this gene

Mammalian mitochondrial ribosomal protein L 24 (39S ribosomal protein L24 mitochondrial) is encoded by nuclear gene MRPL24 and help in protein synthesis within the mitochondrion

Mutations in this gene are associated with erythrocytosis familial type 4

UBCE7IP1 isoform 3 (ZIN)

which is necessary for spliceosomal snRNP assembly in the cytoplasm and pre-mRNA splicing in the nucleus

p53 Polyclonal Antibody, 50ul[BT-AP06832] Molecular Sciences Numerous pseudogenes have been reportedTP53 (tumor protein p53) encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni

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