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CLK3 Polyclonal Antibody, 50ul DNA Fragments ADCK3 encodes a mitochondrial protein

SKU: 23889529317

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CLK3 Polyclonal Antibody, 50ul DNA Fragments ADCK3 encodes a mitochondrial proteinThis gene encodes a protein belonging to the serine threonine type protein kinase family. This protein is a nuclear dual specificity kinase that regulates the intranuclear distribution of the serine arginine rich (SR) family of splicing factors. Two transcript variants encoding different isoforms have been found for this gene. Related pseudogenes are located on chromosomes 1 and 9.

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Description

ADCK3 encodes a mitochondrial protein similar to yeast ABC1

resulting in the synthesis of G(M2) and G(D2)

and mutations in this gene may play a role in amyotrophic lateral sclerosis

These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b)

In addition| the encoded protein interacts with LIS1| the regulatory gamma subunit of platelet activating factor acetylhydrolase| and this interaction is important to proper microtubule function in the developing cortex

CLK3 Polyclonal Antibody, 50ul DNA Fragments ADCK3 encodes a mitochondrial proteinThis gene encodes a protein belonging to the serine threonine type protein kinase family. This protein is a nuclear dual specificity kinase that regulates the intranuclear distribution of the serine arginine rich (SR) family of splicing factors. Two transcript variants encoding different isoforms have been found for this gene. Related pseudogenes are located on chromosomes 1 and 9.

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