HDAC1 (Acetyl Lys220) Rabbit Polyclonal Antibody, 50ul Filtration This enzyme is a microsomal

This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor

and are involved in stem cell development

An important paralog of this gene is FOXE3

Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes

and is required for protein transport from the endoplasmic reticulum (ER) to the Golgi complex

HDAC1 (Acetyl Lys220) Rabbit Polyclonal Antibody, 50ul Filtration This enzyme is a microsomalCatalytic activity: Hydrolysis of an N(6) acetyl lysine residue of a histone to yield a deacetylated histone. Responsible for the deacetylation of lysine residues on the N terminal part of the core histones (H2A H2B H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation cell cycle progression and developmental events. Histone deacetylases act via the formation of large