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Phospho-Akt (S473) Polyclonal Antibody, 20ul[BT-PHS00864] Microplate Mixer Transcripts variants encoding different isoforms

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Phospho-Akt (S473) Polyclonal Antibody, 20ul[BT-PHS00864] Microplate Mixer Transcripts variants encoding different isoformsThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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Description

Transcripts variants encoding different isoforms have been described

The protein associates with the U3 small nucleolar ribonucleoprotein 60-80S complexes and may be involved in pre-rRNA processing

Diseases associated with TRAK2 include amyotrophic lateral sclerosis 2

The protein encoded by TNFRSF1A (TNF receptor superfamily member 1A) is a member of the TNF-receptor superfamily

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Phospho-Akt (S473) Polyclonal Antibody, 20ul[BT-PHS00864] Microplate Mixer Transcripts variants encoding different isoformsThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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